Herpes Simplex Virus 1 Us3 Deletion Mutant is Infective Despite Impaired Capsid Translocation to the Cytoplasm

Herpes Simplex Virus 1 Us3 Deletion Mutant is Infective Despite Impaired Capsid Translocation to the Cytoplasm

Herpes simplex virus 1 (HSV-1) capsids are assembled in the nucleus bud at the inner nuclear membrane into the perinuclear space, acquiring envelope and tegument. In theory, these virions are de-enveloped by fusion of the envelope with the outer nuclear membrane and re-enveloped by Golgi membranes...

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Bibliographic Details
Main Authors: Peter Wild, Sabine Leisinger, Anna Paula de Oliveira, Elisabeth M. Schraner, Andres Kaech, Mathias Ackermann, Kurt Tobler
Format: Article
Language:English
Published: MDPI AG 2015-01-01
Series:Viruses
Subjects:
HSV-1
Us3 protein kinase
envelopment
morphogenesis
electron microscopy
morphometry
Online Access:http://www.mdpi.com/1999-4915/7/1/52

Internet

http://www.mdpi.com/1999-4915/7/1/52

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