Overexpression of Efflux Pumps, Mutations in the Pumps’ Regulators, Chromosomal Mutations, and AAC(6′)-Ib-cr Are Associated With Fluoroquinolone Resistance in Diverse Sequence Types of Neonatal Septicaemic Acinetobacter baumannii: A 7-Year Single Center Study

Overexpression of Efflux Pumps, Mutations in the Pumps’ Regulators, Chromosomal Mutations, and AAC(6′)-Ib-cr Are Associated With Fluoroquinolone Resistance in Diverse Sequence Types of Neonatal Septicaemic Acinetobacter baumannii: A 7-Year Single Center Study

This study investigates susceptibility toward three fluoroquinolones (ciprofloxacin, levofloxacin, moxifloxacin), multiple fluoroquinolone-resistance mechanisms, and epidemiological relationship of neonatal septicaemic Acinetobacter baumannii. Previous studies on fluoroquinolone resistance in A. bau...

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Bibliographic Details
Main Authors: Subhasree Roy, Somdatta Chatterjee, Amrita Bhattacharjee, Pinaki Chattopadhyay, Bijan Saha, Shanta Dutta, Sulagna Basu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Microbiology
Subjects:
A. baumannii
neonatal sepsis
sequence types
ciprofloxacin/levofloxacin/moxifloxacin
RND pumps
AdeRS/AdeL/AdeN
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2021.602724/full

Internet

https://www.frontiersin.org/articles/10.3389/fmicb.2021.602724/full

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