Microneedle biosensors for real-time, minimally invasive drug monitoring of phenoxymethylpenicillin: a first-in-human evaluation in healthy volunteers

Microneedle biosensors for real-time, minimally invasive drug monitoring of phenoxymethylpenicillin: a first-in-human evaluation in healthy volunteers

Summary: Background: Enhanced methods of drug monitoring are required to support the individualisation of antibiotic dosing. We report the first-in-human evaluation of real-time phenoxymethylpenicillin monitoring using a minimally invasive microneedle-based β-lactam biosensor in healthy volunteers....

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Bibliographic Details
Main Authors: Timothy M Rawson, PhD, Sally A N Gowers, PhD, David M E Freeman, PhD, Richard C Wilson, MPharm, Sanjiv Sharma, PhD, Mark Gilchrist, MPharm, Alasdair MacGowan, MD, Andrew Lovering, PhD, Mark Bayliss, PhD, Mathew Kyriakides, MSc, Pantelis Georgiou, PhD, Anthony E G Cass, ProfPhD, Danny O'Hare, PhD, Alison H Holmes, ProfMD
Format: Article
Language:English
Published: Elsevier 2019-11-01
Series:The Lancet: Digital Health
Online Access:http://www.sciencedirect.com/science/article/pii/S2589750019301311

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http://www.sciencedirect.com/science/article/pii/S2589750019301311

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