Modular endolysin of Burkholderia AP3 phage has the largest lysozyme-like catalytic subunit discovered to date and no catalytic aspartate residue

Abstract Endolysins are peptidoglycan-degrading enzymes utilized by bacteriophages to release the progeny from bacterial cells. The lytic properties of phage endolysins make them potential antibacterial agents for medical and industrial applications. Here, we present a comprehensive characterization...

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Bibliographic Details
Main Authors: Barbara Maciejewska, Karol Źrubek, Akbar Espaillat, Magdalena Wiśniewska, Krzysztof P. Rembacz, Felipe Cava, Grzegorz Dubin, Zuzanna Drulis-Kawa
Format: Article
Language:English
Published: Nature Publishing Group 2017-11-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-14797-9