Orf virus interferes with MHC class I surface expression by targeting vesicular transport and Golgi

Orf virus interferes with MHC class I surface expression by targeting vesicular transport and Golgi

<p>Abstract</p> <p>Background</p> <p>The Orf virus (ORFV), a zoonotic Parapoxvirus, causes pustular skin lesions in small ruminants (goat and sheep). Intriguingly, ORFV can repeatedly infect its host, despite the induction of a specific immunity. These immune modulating...

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Bibliographic Details
Main Authors: Rohde Jörg, Emschermann Frederic, Knittler Michael R, Rziha Hanns-Joachim
Format: Article
Language:English
Published: BMC 2012-07-01
Series:BMC Veterinary Research
Subjects:
Orf virus
Parapoxvirus
MHC class I
Subversion
Immunomodulation
Golgi apparatus
Online Access:http://www.biomedcentral.com/1746-6148/8/114

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http://www.biomedcentral.com/1746-6148/8/114

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