DNA damaging agents in ovarian cancer

Epithelial ovarian cancer (EOC) is very sensitive to upfront chemotherapy. This condition is attributable to defects in the DNA damage repair system. Agents that damage DNA are the main drugs used for its treatment. Many EOC cells have DNA repair deficiencies that confer susceptibility to these agen...

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Bibliographic Details
Main Author: Maria-Pilar Barretina-Ginesta
Format: Article
Language:English
Published: Elsevier 2020-08-01
Series:EJC Supplements
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1359634920300057