Genetic variation in <it>TIMP1 </it>but not <it>MMPs </it>predict excess FEV<sub>1 </sub>decline in two general population-based cohorts
<p>Abstract</p> <p>Background</p> <p>An imbalance in Matrix MetalloProteases (MMPs) and Tissue Inhibitors of MMPs (TIMPs) contributes to Chronic Obstructive Pulmonary Disease (COPD) development. Longitudinal studies investigating Single Nucleotide Polymorphisms (SNPs) i...
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2011-04-01
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| Series: | Respiratory Research |
| Online Access: | http://respiratory-research.com/content/12/1/57 |