NAT2 gene polymorphisms and plasma isoniazid concentration in Vietnamese tuberculosis patients

Background: Isoniazid (INH) is one of the most common drug for tuberculosis (TB) treatment and INH acetylation catalysed by non-inducible hepatic enzyme arylamine N-acetyltransferase type 2 (NAT2). The isoniazid acetylation rates, which depends on NAT2 genotypes, is constant in an individual but ca...

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Bibliographic Details
Main Authors: Anh Tuan Le, Nhung Hong Thi Pham, Long Doan Dinh, Luyen Thi Le, Thom Thi Vu
Format: Article
Language:English
Published: Walailak University 2019-11-01
Series:Walailak Journal of Science and Technology
Subjects:
Online Access:http://wjst.wu.ac.th/index.php/wjst/article/view/6517