The Predictive Value of PITX2 DNA Methylation for High-Risk Breast Cancer Therapy: Current Guidelines, Medical Needs, and Challenges

High-risk breast cancer comprises distinct tumor entities such as triple-negative breast cancer (TNBC) which is characterized by lack of estrogen (ER) and progesterone (PR) and the HER2 receptor and breast malignancies which have spread to more than three lymph nodes. For such patients, current (int...

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Bibliographic Details
Main Authors: Michaela Aubele, Manfred Schmitt, Rudolf Napieralski, Stefan Paepke, Johannes Ettl, Magdalena Absmaier, Viktor Magdolen, John Martens, John A. Foekens, Olaf G. Wilhelm, Marion Kiechle
Format: Article
Language:English
Published: Hindawi Limited 2017-01-01
Series:Disease Markers
Online Access:http://dx.doi.org/10.1155/2017/4934608