Purinergic 2X7 Receptor is Involved in the Podocyte Damage of Obesity-Related Glomerulopathy via Activating Nucleotide-Binding and Oligomerization Domain-Like Receptor Protein 3 Inflammasome

Purinergic 2X7 Receptor is Involved in the Podocyte Damage of Obesity-Related Glomerulopathy via Activating Nucleotide-Binding and Oligomerization Domain-Like Receptor Protein 3 Inflammasome

Background: The nucleotide-binding and oligomerization domain-like receptor protein 3 (NLRP3) inflammasome composed of NLRP3, apoptosis-associated speck-like protein containing CARD (ASC), and caspase-1 is engaged in the inflammatory response of many kidney diseases and can be activated by purinergi...

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Bibliographic Details
Main Authors: Xiao-Xia Hou, Hong-Rui Dong, Li-Jun Sun, Min Yang, Hong Cheng, Yi-Pu Chen
Format: Article
Language:English
Published: Wolters Kluwer 2018-01-01
Series:Chinese Medical Journal
Subjects:
Desmin; Nucleotide-Binding and Oligomerization Domain-Like Receptor Protein 3 Inflammasome; Obesity-Related Glomerulopathy; Podocytes; Purinergic 2X7 Receptor
Online Access:http://www.cmj.org/article.asp?issn=0366-6999;year=2018;volume=131;issue=22;spage=2713;epage=2725;aulast=Hou

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http://www.cmj.org/article.asp?issn=0366-6999;year=2018;volume=131;issue=22;spage=2713;epage=2725;aulast=Hou

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