Receptor pre-clustering and T cell responses: insights into molecular mechanisms
T~cell activation, initiated by T~cell receptor (TCR) mediated<br/> recognition of pathogen derived peptides presented by major<br/> histocompatibility complex class I or II molecules (pMHC), shows<br/> exquisite specificity and sensitivity, even though the TCR-pMHC<br/>...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2014-04-01
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Series: | Frontiers in Immunology |
Subjects: | |
Online Access: | http://journal.frontiersin.org/Journal/10.3389/fimmu.2014.00132/full |