Receptor pre-clustering and T cell responses: insights into molecular mechanisms

Receptor pre-clustering and T cell responses: insights into molecular mechanisms

T~cell activation, initiated by T~cell receptor (TCR) mediated<br/> recognition of pathogen derived peptides presented by major<br/> histocompatibility complex class I or II molecules (pMHC), shows<br/> exquisite specificity and sensitivity, even though the TCR-pMHC<br/>...

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Bibliographic Details
Main Authors: Mario eCastro, Hisse M van Santen, María eFerez, Balbino eAlarcón, Grant D Lythe, Carmen eMolina-Paris
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-04-01
Series:Frontiers in Immunology
Subjects:
signalling
T cell receptor
clustering
memory T cells
stochastic dynamics
naive T cells
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2014.00132/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fimmu.2014.00132/full

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