Seven-Membered Rings through Metal-Free Rearrangement Mediated by Hypervalent Iodine

Seven-Membered Rings through Metal-Free Rearrangement Mediated by Hypervalent Iodine

A versatile and metal-free approach for the synthesis of carbocycles and of heterocycles bearing seven- and eight-membered rings is described. The strategy is based on ring expansion of 1-vinylcycloalkanols (or the corresponding silyl or methyl ether) mediated by the hypervalent iodine reagent HTIB...

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Bibliographic Details
Main Authors: Siguara Bastos Lemos Silva, Adriana Della Torre, João Ernesto de Carvalho, Ana Lúcia Tasca Gois Ruiz, Luiz F. Silva
Format: Article
Language:English
Published: MDPI AG 2015-01-01
Series:Molecules
Subjects:
hypervalent iodine
ring expansion
rearrangement
seven-membered ring
antiproliferative activity
Online Access:http://www.mdpi.com/1420-3049/20/1/1475

Internet

http://www.mdpi.com/1420-3049/20/1/1475

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