Molecular Regulation of Auditory Hair Cell Death and Approaches to Protect Sensory Receptor Cells and/or Stimulate Repair Following Acoustic Trauma

Loss of auditory sensory hair cells is the most common cause of hearing loss. This review addresses the signaling pathways that are involved in the programmed and necrotic cell death of auditory hair cells that occur in response to ototoxic and traumatic stressor events. The roles of inflammatory pr...

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Bibliographic Details
Main Authors: Christine T DINH, Stefania eGONCALVES, Esperanza eBAS, Thomas R VAN DE WATER, Azel eZINE
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-03-01
Series:Frontiers in Cellular Neuroscience
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fncel.2015.00096/full