Genome variation and conserved regulation identify genomic regions responsible for strain specific phenotypes in rat

Genome variation and conserved regulation identify genomic regions responsible for strain specific phenotypes in rat

Abstract Background The genomes of laboratory rat strains are characterised by a mosaic haplotype structure caused by their unique breeding history. These mosaic haplotypes have been recently mapped by extensive sequencing of key strains. Comparison of genomic variation between two closely related r...

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Bibliographic Details
Main Authors: David Martín-Gálvez, Denis Dunoyer de Segonzac, Man Chun John Ma, Anne E. Kwitek, David Thybert, Paul Flicek
Format: Article
Language:English
Published: BMC 2017-12-01
Series:BMC Genomics
Subjects:
Metabolic syndrome
Genome regulation
Evolution
Online Access:http://link.springer.com/article/10.1186/s12864-017-4351-9

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http://link.springer.com/article/10.1186/s12864-017-4351-9

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