N-Acetyl-cysteine causes analgesia by reinforcing the endogenous activation of type-2 metabotropic glutamate receptors

N-Acetyl-cysteine causes analgesia by reinforcing the endogenous activation of type-2 metabotropic glutamate receptors

<p>Abstract</p> <p>Background</p> <p>Pharmacological activation of type-2 metabotropic glutamate receptors (mGlu2 receptors) causes analgesia in experimental models of inflammatory and neuropathic pain. Presynaptic mGlu2 receptors are activated by the glutamate released...

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Bibliographic Details
Main Authors: Bernabucci Matteo, Notartomaso Serena, Zappulla Cristina, Fazio Francesco, Cannella Milena, Motolese Marta, Battaglia Giuseppe, Bruno Valeria, Gradini Roberto, Nicoletti Ferdinando
Format: Article
Language:English
Published: SAGE Publishing 2012-10-01
Series:Molecular Pain
Subjects:
Cystine/glutamate antiporter
N-acetyl-cysteine
mGlu2 receptors
Analgesia
AGS3
Online Access:http://www.molecularpain.com/content/8/1/77

Internet

http://www.molecularpain.com/content/8/1/77

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