Epigenome Mapping Identifies Tumor-Specific Gene Expression in Primary Rectal Cancer

Epigenome Mapping Identifies Tumor-Specific Gene Expression in Primary Rectal Cancer

Epigenetic alterations play a central role in cancer development and progression. The acetylation of histone 3 at lysine 27 (H3K27ac) specifically marks active genes. While chromatin immunoprecipitation (ChIP) followed by next-generation sequencing (ChIP-seq) analyses are commonly performed in cell...

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Bibliographic Details
Main Authors: Hannah Flebbe, Feda H. Hamdan, Vijayalakshmi Kari, Julia Kitz, Jochen Gaedcke, B. Michael Ghadimi, Steven A. Johnsen, Marian Grade
Format: Article
Language:English
Published: MDPI AG 2019-08-01
Series:Cancers
Subjects:
ChIP-seq
chromatin
epigenetics
histone modification
H3K27ac
rectal cancer
gene expression
Online Access:https://www.mdpi.com/2072-6694/11/8/1142

Internet

https://www.mdpi.com/2072-6694/11/8/1142

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