Fatty Acid and Lipopolysaccharide Effect on Beta Cells Proteostasis and its Impact on Insulin Secretion

Fatty Acid and Lipopolysaccharide Effect on Beta Cells Proteostasis and its Impact on Insulin Secretion

Metabolic overload by saturated fatty acids (SFA), which comprises &#946;-cell function, and impaired glucose-stimulated insulin secretion are frequently observed in patients suffering from obesity and type 2 diabetes mellitus. The increase of intracellular Ca<sup>2+</sup> triggers i...

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Bibliographic Details
Main Authors: Paloma Acosta-Montaño, Eustolia Rodríguez-Velázquez, Esmeralda Ibarra-López, Héctor Frayde-Gómez, Jaime Mas-Oliva, Blanca Delgado-Coello, Ignacio A. Rivero, Manuel Alatorre-Meda, Jorge Aguilera, Lizbeth Guevara-Olaya, Victor García-González
Format: Article
Language:English
Published: MDPI AG 2019-08-01
Series:Cells
Subjects:
fatty acids
lipopolysaccharides
β-cells
proteostasis
insulin secretion
Online Access:https://www.mdpi.com/2073-4409/8/8/884

Internet

https://www.mdpi.com/2073-4409/8/8/884

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