Long-Chain Acetylenic Ketones from the Micronesian Sponge Haliclona sp. Importance of the 1-yn-3-ol Group for Antitumor Activity

Abstract: Two new long-chain C33 polyacetylenic compounds, halicynones A and B were isolated from the marine sponge Haliclona sp. along with known analogs. The known compound pellynol A possessing a 1-yn-3-ol terminus, exhibited strong antitumor activity against the human colon tumor cell line HCT-1...

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Bibliographic Details
Main Authors: Guang-Xiong Zhou, Tadeusz F. Molinski
Format: Article
Language:English
Published: MDPI AG 2003-11-01
Series:Marine Drugs
Subjects:
Online Access:http://www.mdpi.com/1660-3397/1/1/46/