Effectiveness of Whole, Inactivated, Low Pathogenicity Influenza A(H7N9) Vaccine against Antigenically Distinct, Highly Pathogenic H7N9 Virus

The recent emergence of highly pathogenic influenza A(H7N9) variants poses a great risk to humans. We show that ferrets vaccinated with low pathogenicity H7N9 virus vaccine do not develop severe symptoms after infection with an antigenically distinct, highly pathogenic H7N9 virus. These results demo...

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Bibliographic Details
Main Authors: Masato Hatta, Gongxun Zhong, Shiho Chiba, Tiago J.S. Lopes, Gabriele Neumann, Yoshihiro Kawaoka
Format: Article
Language:English
Published: Centers for Disease Control and Prevention 2018-10-01
Series:Emerging Infectious Diseases
Subjects:
Online Access:https://wwwnc.cdc.gov/eid/article/24/10/18-0403_article