Baicalein Inhibits MMPs Expression via a MAPK-Dependent Mechanism in Chondrocytes

Baicalein Inhibits MMPs Expression via a MAPK-Dependent Mechanism in Chondrocytes

Background: Baicalein is a flavonoid isolated from Scutellaria baicalensis Georgi. Here, we investigated the anti-osteoarthritic effect of baicalein in vitro and in vivo. Methods: Interleukin-1 beta (IL-1β)-induced chondrocytes were treated with different concentrations of baicalein, real-time PCR a...

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Bibliographic Details
Main Authors: Wei-Ping Chen, Yan Xiong, Peng-Fei Hu, Jia-Peng Bao, Li-Dong Wu
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2015-05-01
Series:Cellular Physiology and Biochemistry
Subjects:
Interleukin-1β
Matrix metalloproteinase
Baicalein
Osteoarthritis
Chondrocytes
Online Access:http://www.karger.com/Article/FullText/374075

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http://www.karger.com/Article/FullText/374075

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