Karyopherina 2 knockdown inhibits osteosarcoma cell proliferation and angiogenesis in mice by suppressing Sox2 expression

Karyopherina 2 knockdown inhibits osteosarcoma cell proliferation and angiogenesis in mice by suppressing Sox2 expression

Objective To explore the effect of karyopherina 2 (KPNA2) knockdown on osteosarcoma cell proliferation and angiogenesis and the possible molecular mechanism. Methods We transfected Saos-2 cells with a Sh-KPNA2 lentiviral vector or a control vector (Sh-Control) to observe the effect of KPNA2 knockdow...

Full description

Bibliographic Details
Main Authors: GE Qiaofeng, ZHANG Long, SUN Xiaojuan, LYU Zhi
Format: Article
Language:zho
Published: Editorial Office of Journal of Third Military Medical University 2019-07-01
Series:Di-san junyi daxue xuebao
Subjects:
karyopherina 2
osteosarcoma cell
cell proliferation
tumor angiogenesis
sox2
nude mice
Online Access:http://aammt.tmmu.edu.cn/Upload/rhtml/201901004.htm

Internet

http://aammt.tmmu.edu.cn/Upload/rhtml/201901004.htm

Similar Items