Synthesis, physical and chemical properties of 7-methylxanthine derivatives

It is known that 8-aminosubstituted N-methylated xanthines are dipeptidyl peptidase-4 antagonists, ligands for 5-hydroxytryptamine receptors and exert diverse biological effects. Previously, it was found that the 7-alkyl-8-piperazinoxanthines exhibit diuretic, depremic, analgesic effect. Some amino...

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Bibliographic Details
Main Authors: M. I. Romanenko, O. P. Dolhikh, D. H. Ivanchenko, K. V. Aleksandrova
Format: Article
Language:English
Published: Zaporozhye State Medical University 2017-12-01
Series:Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki
Subjects:
Online Access:http://pharmed.zsmu.edu.ua/article/view/113546/110367