The Challenges of Informed Consent in High-Stakes, Randomized Oncology Trials: A Systematic Review

Importance. Oncology trials often entail high-stakes interventions where potential for morbidity and fatal side effects, and for life-prolongation or cure, intensify bioethical issues surrounding informed consent. These challenges are compounded in multistage randomized trials, which are prevalent i...

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Bibliographic Details
Main Authors: Julia M. Nathe, Elizabeth F. Krakow
Format: Article
Language:English
Published: SAGE Publishing 2019-03-01
Series:MDM Policy & Practice
Online Access:https://doi.org/10.1177/2381468319840322