The impact of gallic acid on the methotrexate-induced kidney damage in rats

Prolonged use of an antineoplastic agent methotrexate (MTX), can cause numerous side effects such as nephrotoxicity. The aim of this study was to examine the effects of MTX on kidneys and demonstrate the protective effects of gallic acid (GA). Twenty-four, male, rats distributed into three groups. E...

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Bibliographic Details
Main Authors: Halil Asci, Ozlem Ozmen, Hamit Yasar Ellidag, Bunyamin Aydin, Ercan Bas, Necat Yilmaz
Format: Article
Language:English
Published: Elsevier 2017-10-01
Series:Journal of Food and Drug Analysis
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1021949817300911