Characterization of Five Novel Anti-MRSA Compounds Identified Using a Whole-Animal <i>Caenorhabditis elegans</i>/<i>Galleria mellonella</i> Sequential-Screening Approach

Characterization of Five Novel Anti-MRSA Compounds Identified Using a Whole-Animal <i>Caenorhabditis elegans</i>/<i>Galleria mellonella</i> Sequential-Screening Approach

There is a significant need to combat the growing challenge of antibacterial drug resistance. We have previously developed a whole-animal dual-screening platform that first used the nematode <i>Caenorhabditis elegans</i>, to identify low-toxicity antibacterial hits in a high-throughput f...

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Bibliographic Details
Main Authors: Rajamohammed Khader, Nagendran Tharmalingam, Biswajit Mishra, LewisOscar Felix, Frederick M. Ausubel, Michael J. Kelso, Eleftherios Mylonakis
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:Antibiotics
Subjects:
antibiotic
high-throughput screening (HTS), MRSA
MIC
<i>Caenorhabditis elegans</i>
<i>Galleria mellonella</i>
Online Access:https://www.mdpi.com/2079-6382/9/8/449

Internet

https://www.mdpi.com/2079-6382/9/8/449

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