eIF3a Regulation of NHEJ Repair Protein Synthesis and Cellular Response to Ionizing Radiation

Translation initiation in protein synthesis regulated by eukaryotic initiation factors (eIFs) is a crucial step in controlling gene expression. eIF3a has been shown to regulate protein synthesis and cellular response to treatments by anticancer agents including cisplatin by regulating nucleotide exc...

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Bibliographic Details
Main Authors: Rima Tumia, Chao J. Wang, Tianhan Dong, Shijie Ma, Jenny Beebe, Juan Chen, Zizheng Dong, Jing-Yuan Liu, Jian-Ting Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-08-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fcell.2020.00753/full