Downregulation of CR6-interacting factor 1 suppresses keloid fibroblast growth via the TGF-β/Smad signaling pathway

Abstract Keloids are a type of aberrant skin scarring characterized by excessive accumulation of collagen and extracellular matrix (ECM), arising from uncontrolled wound healing responses. While typically non-pathogenic, keloids are occasionally regarded as a form of benign tumor. CR6-interacting fa...

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Bibliographic Details
Main Authors: Harsha Nagar, Sungmin Kim, Ikjun Lee, Seonhee Kim, Su-Jeong Choi, Shuyu Piao, Byeong Hwa Jeon, Sang-Ha Oh, Cuk-Seong Kim
Format: Article
Language:English
Published: Nature Publishing Group 2021-01-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-020-79785-y