BNIP3L-Dependent Mitophagy Promotes HBx-Induced Cancer Stemness of Hepatocellular Carcinoma Cells via Glycolysis Metabolism Reprogramming

BNIP3L-Dependent Mitophagy Promotes HBx-Induced Cancer Stemness of Hepatocellular Carcinoma Cells via Glycolysis Metabolism Reprogramming

Hepatitis B virus (HBV) is one of predisposing factors for hepatocellular carcinoma (HCC). The role of HBV x protein (HBx) in mediating the induction and maintenance of cancer stemness during HBV-related HCC attracts considerable attention, but the exact mechanism has not been clearly elucidated. He...

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Bibliographic Details
Main Authors: Yuan-Yuan Chen, Wei-Hua Wang, Lin Che, You Lan, Li-Yin Zhang, Deng-Lin Zhan, Zi-Yan Huang, Zhong-Ning Lin, Yu-Chun Lin
Format: Article
Language:English
Published: MDPI AG 2020-03-01
Series:Cancers
Subjects:
hepatitis b virus x protein
liver cancer stem cells
bnip3l
mitophagy
glycolysis metabolism reprogramming
Online Access:https://www.mdpi.com/2072-6694/12/3/655

Internet

https://www.mdpi.com/2072-6694/12/3/655

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