The first example of the Fischer–Hepp type rearrangement in pyrimidines

A N-nitroso moiety can be used for the activation of chloropyrimidines toward a nucleophilic substitution reaction with amines. The subsequent treatment of the obtained products with aq H2SO4 can lead to either N-denitrosation to obtain 4,6-pyrimidinediamines or to a Fischer–Hepp type rearrangement...

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Bibliographic Details
Main Authors: Inga Cikotiene, Mantas Jonusis, Virginija Jakubkiene
Format: Article
Language:English
Published: Beilstein-Institut 2013-09-01
Series:Beilstein Journal of Organic Chemistry
Subjects:
Online Access:https://doi.org/10.3762/bjoc.9.212