Inactivation of FOXO1 induces T follicular cell polarization and involves angioimmunoblastic T cell lymphoma

Inactivation of FOXO1 induces T follicular cell polarization and involves angioimmunoblastic T cell lymphoma

ObjectiveAngioimmunoblastic T cell lymphoma (AITL) is an aggressive form of non-Hodgkin lymphoma derived from mature T cells. However, the underlying pathogenesis of AITL remains unresolved. We aimed to explore the role of FOXO1-mediated signaling in the tumorigenesis and progression of AITL.Methods...

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Bibliographic Details
Main Authors: Meifang Xu, Fei Wang, Hong Chen, Lin Liu, Wenwen Liu, Yinghong Yang, Qiaoling Zheng, Lihong Zhang, Xiaoxuan Li, Suxia Lin, Shengbing Zang
Format: Article
Language:English
Published: China Anti-Cancer Association 2019-12-01
Series:Cancer Biology & Medicine
Subjects:
angioimmunoblastic t cell lymphoma
foxo1
inactivation
differentiation
Online Access:http://www.cancerbiomed.org/index.php/cocr/article/view/1511

Internet

http://www.cancerbiomed.org/index.php/cocr/article/view/1511

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