The Genetic and Molecular Mechanisms of Congenital Hyperinsulinism

The Genetic and Molecular Mechanisms of Congenital Hyperinsulinism

Congenital hyperinsulinism (CHI) is a heterogenous and complex disorder in which the unregulated insulin secretion from pancreatic beta-cells leads to hyperinsulinaemic hypoglycaemia. The severity of hypoglycaemia varies depending on the underlying molecular mechanism and genetic defects. The geneti...

Full description

Bibliographic Details
Main Authors: Sonya Galcheva, Hüseyin Demirbilek, Sara Al-Khawaga, Khalid Hussain
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-02-01
Series:Frontiers in Endocrinology
Subjects:
hyperinsulinism
hypoglycaemia
molecular mechanisms
genetics
mutation
Online Access:https://www.frontiersin.org/article/10.3389/fendo.2019.00111/full

Internet

https://www.frontiersin.org/article/10.3389/fendo.2019.00111/full

Similar Items