The Genetic and Molecular Mechanisms of Congenital Hyperinsulinism
Congenital hyperinsulinism (CHI) is a heterogenous and complex disorder in which the unregulated insulin secretion from pancreatic beta-cells leads to hyperinsulinaemic hypoglycaemia. The severity of hypoglycaemia varies depending on the underlying molecular mechanism and genetic defects. The geneti...
Main Authors: | Sonya Galcheva, Hüseyin Demirbilek, Sara Al-Khawaga, Khalid Hussain |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2019-02-01
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Series: | Frontiers in Endocrinology |
Subjects: | |
Online Access: | https://www.frontiersin.org/article/10.3389/fendo.2019.00111/full |
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