Chicken cGAS Senses Fowlpox Virus Infection and Regulates Macrophage Effector Functions

Chicken cGAS Senses Fowlpox Virus Infection and Regulates Macrophage Effector Functions

The anti-viral immune response is dependent on the ability of infected cells to sense foreign nucleic acids. In multiple species, the pattern recognition receptor (PRR) cyclic GMP-AMP synthase (cGAS) senses viral DNA as an essential component of the innate response. cGAS initiates a range of signali...

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Bibliographic Details
Main Authors: Marisa Oliveira, Damaris Ribeiro Rodrigues, Vanaique Guillory, Emmanuel Kut, Efstathios S. Giotis, Michael A. Skinner, Rodrigo Guabiraba, Clare E. Bryant, Brian J. Ferguson
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Immunology
Subjects:
DNA
fowlpox
chicken
macrophages
cyclic GMP-AMP synthase
stimulator of interferon genes
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2020.613079/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2020.613079/full

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