Clarifying the Translational Pausing Landscape in Bacteria by Ribosome Profiling

The rate of protein synthesis varies according to the mRNA sequence in ways that affect gene expression. Global analysis of translational pausing is now possible with ribosome profiling. Here, we revisit an earlier report that Shine-Dalgarno sequences are the major determinant of translational pausi...

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Bibliographic Details
Main Authors: Fuad Mohammad, Christopher J. Woolstenhulme, Rachel Green, Allen R. Buskirk
Format: Article
Language:English
Published: Elsevier 2016-02-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124715015296