Immunogenicity and Induction of Functional Antibodies in Rabbits Immunized with a Trivalent Typhoid-Invasive Nontyphoidal Salmonella Glycoconjugate Formulation

Immunogenicity and Induction of Functional Antibodies in Rabbits Immunized with a Trivalent Typhoid-Invasive Nontyphoidal Salmonella Glycoconjugate Formulation

Typhoid fever due to Salmonella Typhi and invasive nontyphoidal Salmonella (iNTS) infections caused by serovars Enteritidis (SE) and Typhimurium (STm) are major pediatric health problems in sub-Saharan Africa. Typhoid has high complication rates, and iNTS infections have high case fatality rates; mo...

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Bibliographic Details
Main Authors: Scott M. Baliban, Jessica C. Allen, Brittany Curtis, Mohammed N. Amin, Andrew Lees, R. Nageswara Rao, Gangadhara Naidu, Ramasamy Venkatesan, D. Yogeswara Rao, Vadrevu Krishna Mohan, Krishna M. Ella, Myron M. Levine, Raphael Simon
Format: Article
Language:English
Published: MDPI AG 2018-07-01
Series:Molecules
Subjects:
lipopolysaccharide
Vi
glycoconjugate
antibody
Salmonella
flagellin
vaccine
iNTS
typhoid
Online Access:http://www.mdpi.com/1420-3049/23/7/1749

Internet

http://www.mdpi.com/1420-3049/23/7/1749

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