CD22 Blockage Restores Age-Related Impairments of Microglia Surveillance Capacity

CD22 Blockage Restores Age-Related Impairments of Microglia Surveillance Capacity

Microglia, the innate immune cells of the brain, are essential for maintaining homeostasis by their ramified, highly motile processes and for orchestrating the immune response to pathological stimuli. They are implicated in several neurodegenerative diseases like Alzheimer’s and Parkinson’s disease....

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Bibliographic Details
Main Authors: Vanessa Aires, Claire Coulon-Bainier, Anto Pavlovic, Martin Ebeling, Roland Schmucki, Christophe Schweitzer, Erich Kueng, Simon Gutbier, Eva Harde
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Immunology
Subjects:
CD22
microglia
two-photon imaging
surveillance
iPSC macrophages
phagocytosis
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.684430/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.684430/full

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