CD22 Blockage Restores Age-Related Impairments of Microglia Surveillance Capacity
Microglia, the innate immune cells of the brain, are essential for maintaining homeostasis by their ramified, highly motile processes and for orchestrating the immune response to pathological stimuli. They are implicated in several neurodegenerative diseases like Alzheimer’s and Parkinson’s disease....
Main Authors: | Vanessa Aires, Claire Coulon-Bainier, Anto Pavlovic, Martin Ebeling, Roland Schmucki, Christophe Schweitzer, Erich Kueng, Simon Gutbier, Eva Harde |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2021-06-01
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Series: | Frontiers in Immunology |
Subjects: | |
Online Access: | https://www.frontiersin.org/articles/10.3389/fimmu.2021.684430/full |
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