Injectable, macroporous scaffolds for delivery of therapeutic genes to the injured spinal cord

Biomaterials are being developed as therapeutics for spinal cord injury (SCI) that can stabilize and bridge acute lesions and mediate the delivery of transgenes, providing a localized and sustained reservoir of regenerative factors. For clinical use, direct injection of biomaterial scaffolds is pref...

Full description

Bibliographic Details
Main Authors: Arshia Ehsanipour, Mayilone Sathialingam, Laila M. Rad, Joseph de Rutte, Rebecca D. Bierman, Jesse Liang, Weikun Xiao, Dino Di Carlo, Stephanie K. Seidlits
Format: Article
Language:English
Published: AIP Publishing LLC 2021-03-01
Series:APL Bioengineering
Online Access:http://dx.doi.org/10.1063/5.0035291