Study of the IL-4 and IL-4δ2 interaction with the IL-4R receptors of the I and II types in silico and the effect on the functional activity of mononuclear cells in vitro

Study of the IL-4 and IL-4δ2 interaction with the IL-4R receptors of the I and II types in silico and the effect on the functional activity of mononuclear cells in vitro

Alternatively spliced interleukins are very actively studied over the last years. Splice form of IL-4 — IL-4δ2 has antagonistic effects to its full form on proliferative activity of human mononuclear blood cells and their IL-6 production. Antagonistic effects between IL-4 and IL-4δ2 were confirmed a...

Full description

Bibliographic Details
Main Authors: K. V. Goremykin, A. N. Silkov, B. V. Shilov, V. Yu. Serebrov, A. E. Sazonov, S. V. Sennikov
Format: Article
Language:English
Published: Siberian State Medical University (Tomsk) 2010-06-01
Series:Bûlleten' Sibirskoj Mediciny
Subjects:
il-4δ2
il-4
autodock
mononuclear blood cells
b-lymphocytes
Online Access:https://bulletin.tomsk.ru/jour/article/view/1593

Internet

https://bulletin.tomsk.ru/jour/article/view/1593

Similar Items