The Immune Protein Calprotectin Impacts Clostridioides difficile Metabolism through Zinc Limitation

The Immune Protein Calprotectin Impacts Clostridioides difficile Metabolism through Zinc Limitation

Clostridioides difficile infection (CDI) is the leading cause of postantibiotic nosocomial infection. Antibiotic therapy can be successful, yet up to one-third of individuals suffer from recurrent infections. Understanding the mechanisms controlling C. difficile colonization is paramount in designin...

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Bibliographic Details
Main Authors: Christopher A. Lopez, William N. Beavers, Andy Weiss, Reece J. Knippel, Joseph P. Zackular, Walter Chazin, Eric P. Skaar
Format: Article
Language:English
Published: American Society for Microbiology 2019-11-01
Series:mBio
Subjects:
clostridioides difficile
stickland fermentation
calprotectin
proline
zinc
Online Access:https://doi.org/10.1128/mBio.02289-19

Internet

https://doi.org/10.1128/mBio.02289-19

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