RAMBO-K: Rapid and Sensitive Removal of Background Sequences from Next Generation Sequencing Data.

The assembly of viral or endosymbiont genomes from Next Generation Sequencing (NGS) data is often hampered by the predominant abundance of reads originating from the host organism. These reads increase the memory and CPU time usage of the assembler and can lead to misassemblies.We developed RAMBO-K...

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Bibliographic Details
Main Authors: Simon H Tausch, Bernhard Y Renard, Andreas Nitsche, Piotr Wojciech Dabrowski
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4574938?pdf=render