Expression Analysis of Canine CMTM6 and CMTM4 as Potential Regulators of the PD-L1 Protein in Canine Cancers

Expression Analysis of Canine CMTM6 and CMTM4 as Potential Regulators of the PD-L1 Protein in Canine Cancers

Cancer is one of the most significant causes of death in dogs. Antibody drugs targeting the PD-1/PD-L1 axis represent a promising immunotherapy for both human and canine cancers. However, the regulation mechanisms of PD-L1 expression in canine cancers require further investigation to better understa...

Full description

Bibliographic Details
Main Authors: Hiroto Takeuchi, Satoru Konnai, Naoya Maekawa, Erina Minato, Yoshiki Ichikawa, Atsushi Kobayashi, Tomohiro Okagawa, Shiro Murata, Kazuhiko Ohashi
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-06-01
Series:Frontiers in Veterinary Science
Subjects:
canine
CMTM6
CMTM4
PD-L1
molecular identification
cancer immunotherapy
Online Access:https://www.frontiersin.org/article/10.3389/fvets.2020.00330/full

Internet

https://www.frontiersin.org/article/10.3389/fvets.2020.00330/full

Similar Items