The lncRNA MALAT1/miR-30/Spastin Axis Regulates Hippocampal Neurite Outgrowth

The lncRNA MALAT1/miR-30/Spastin Axis Regulates Hippocampal Neurite Outgrowth

Spastin, a microtubule-severing enzyme, is important for neurite outgrowth. However, the mechanisms underlying the post-transcriptional regulation of spastin during microtubule-related processes are largely unknown. We demonstrated that the spastin expression level is controlled by a long non-coding...

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Bibliographic Details
Main Authors: Tao Jiang, Zhenbin Cai, Zhisheng Ji, Jianyu Zou, Zhi Liang, Guowei Zhang, Yaozhong Liang, Hongsheng Lin, Minghui Tan
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-10-01
Series:Frontiers in Cellular Neuroscience
Subjects:
neurite outgrowth
spastin
miR-30
MALAT1
microtubule severing
Online Access:https://www.frontiersin.org/articles/10.3389/fncel.2020.555747/full

Internet

https://www.frontiersin.org/articles/10.3389/fncel.2020.555747/full

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