Bayesian refinement of protein structures and ensembles against SAXS data using molecular dynamics.

Small-angle X-ray scattering is an increasingly popular technique used to detect protein structures and ensembles in solution. However, the refinement of structures and ensembles against SAXS data is often ambiguous due to the low information content of SAXS data, unknown systematic errors, and unkn...

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Bibliographic Details
Main Authors: Roman Shevchuk, Jochen S Hub
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-10-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC5662244?pdf=render