Synthesis of New N-Arylpyrimidin-2-amine Derivatives Using a Palladium Catalyst

Synthesis of New N-Arylpyrimidin-2-amine Derivatives Using a Palladium Catalyst

New N-aryl-4-(pyridin-3-yl)pyrimidin-2-amine derivatives were synthesizedfrom the corresponding amines, applying optimized Buchwald-Hartwig aminationconditions using dichlorobis(triphenylphosphine)Pd(II), xantphos and sodium tertbutoxidein refluxing toluene under a nitrogen atmosphere. The target N-...

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Bibliographic Details
Main Authors: So Ha Lee, Jae Chun Ryu, Ibrahim Mustafa El-Deeb
Format: Article
Language:English
Published: MDPI AG 2008-04-01
Series:Molecules
Subjects:
Palladium catalyst
N-arylation
aminopyrimidine
xantphos
Suzuki coupling
Buchwald-Hartwig amination.
Online Access:http://www.mdpi.com/1420-3049/13/4/818/

Internet

http://www.mdpi.com/1420-3049/13/4/818/

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