Selenoprotein P Regulates Synaptic Zinc and Reduces Tau Phosphorylation

Selenoprotein P Regulates Synaptic Zinc and Reduces Tau Phosphorylation

Selenoprotein P (SELENOP1) is a selenium-rich antioxidant protein involved in extracellular transport of selenium (Se). SELENOP1 also has metal binding properties. The trace element Zinc (Zn2+) is a neuromodulator that can be released from synaptic terminals in the brain, primarily from a subset of...

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Bibliographic Details
Main Authors: Arlene C. P. Kiyohara, Daniel J. Torres, Ayaka Hagiwara, Jenna Pak, Rachel H. L. H. Rueli, C. William R. Shuttleworth, Frederick P. Bellinger
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-07-01
Series:Frontiers in Nutrition
Subjects:
Selenoprotein P
zinc
Alzheimer's disease
tau
selenium
Online Access:https://www.frontiersin.org/articles/10.3389/fnut.2021.683154/full

Internet

https://www.frontiersin.org/articles/10.3389/fnut.2021.683154/full

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