Conserved Two-Step Regulatory Mechanism of Human Epithelial Differentiation

Human epithelia are organized in a hierarchical structure, where stem cells generate terminally differentiated cells via intermediate progenitors. This two-step differentiation process is conserved in all tissues, but it is not known whether a common gene set contributes to its regulation. Here, we...

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Bibliographic Details
Main Authors: Jayant K. Rane, Alastair P. Droop, Davide Pellacani, Euan S. Polson, Matthew S. Simms, Anne T. Collins, Leo S.D. Caves, Norman J. Maitland
Format: Article
Language:English
Published: Elsevier 2014-02-01
Series:Stem Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2213671114000022