The use of polyvinyl alcohol glutaraldehyde as solid-phase in ELISA for plague

Discs of polyvinyl alcohol cross-linked with glutaraldehyde were synthesized under acid catalysis (H2SO4). Then, the antigen F1 purified from Yersinia pestis was covalently linked to this modified polymer. Afterwards, an enzyme-linked immunosorbent assay (ELISA) was established for the diagnosis of...

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Main Authors: Aureci Maria Araujo, André Tavares S Petribú, Gustavo Henrique T Sales Barbosa, José Ricardo P Diniz, Alzira MP de Almeida, Walter Mendes Azevedo, Elizabeth Malagueño, Luiz B Carvalho Jr
Format: Article
Language:English
Published: Instituto Oswaldo Cruz, Ministério da Saúde 1996-04-01
Series:Memórias do Instituto Oswaldo Cruz.
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02761996000200014