Dysfunctional mTORC1 Signaling: A Convergent Mechanism between Syndromic and Nonsyndromic Forms of Autism Spectrum Disorder?

Whereas autism spectrum disorder (ASD) exhibits striking heterogeneity in genetics and clinical presentation, dysfunction of mechanistic target of rapamycin complex 1 (mTORC1) signaling pathway has been identified as a molecular feature common to several well-characterized syndromes with high preval...

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Bibliographic Details
Main Authors: Juliana Magdalon, Sandra M. Sánchez-Sánchez, Karina Griesi-Oliveira, Andréa L. Sertié
Format: Article
Language:English
Published: MDPI AG 2017-03-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:http://www.mdpi.com/1422-0067/18/3/659