Role of T cell – glial cell interactions in creating and amplifying Central Nervous System inflammation and Multiple Sclerosis disease symptoms

Role of T cell – glial cell interactions in creating and amplifying Central Nervous System inflammation and Multiple Sclerosis disease symptoms

Multiple Sclerosis (MS) is an inflammatory disease of the Central Nervous System (CNS) that causes the demyelination of nerve cells and destroys oligodendrocytes, neurons and axons. Historically, MS has been thought of as a T cell-mediated autoimmune disease of CNS white matter. However, recent stud...

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Bibliographic Details
Main Authors: Eric S. Huseby, Daisuke eKamimura, Yasunobu eArima, Caitlin S Parello, Katsuhiro eSasaki, Masaaki eMurakami
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-08-01
Series:Frontiers in Cellular Neuroscience
Subjects:
Astrocytes
Autoimmunity
Cerebellum
Glial Fibrillary Acidic Protein
Multiple Sclerosis
T cell
Online Access:http://journal.frontiersin.org/Journal/10.3389/fncel.2015.00295/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fncel.2015.00295/full

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